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Before being validated and applied in breast cancer, SLNB was demonstrated to be feasible in parotid tumors, penile cancer, and melanoma [ 17 ]. Sentinel lymph node biopsy after neoadjuvant chemotherapy for advanced breast cancer:

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All patients were supposed to receive adjuvant radiation through tangential fields. In a recent meta-analysis of six retrospective studies comprising 1, patients undergoing 1, prophylactic mastectomies, occult cancer was found in 21 of specimens 1. Hematol Oncol Clin North Am.

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Meta-analysis of sentinel lymph node biopsy at the time of prophylactic mastectomy of the breast. Evolution of axillary nodal staging in breast cancer: Locoregional recurrence after breast cancer surgery: